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카티스템 | 2021-02-20 Allogenic Human Umbilical Cord Blood-Derived Mesenchymal Stem Cells Are More Effective Than Bone Marrow Aspiration Concentrate for Cartilage Regeneration After High Tibial Osteotomy in Medial Unicompartmental Osteoarthritis of Knee
무릎 슬관절 내측 골관절염 환자에서 BMAC 대비 카티스템 투여가 연골재생에 더 효과적임.· 발행정보 | Arthroscopy. 2021 Aug;37(8):2521-2530. doi: 10.1016/j.arthro.2021.02.022. · 저자 | Nam-Hun Lee, Seung-Min Na, Hyeon-Wook Ahn, Joon-Kyoo Kang, Jong-Keun Seon, Eun-Kyoo Song |
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카티스템 | 2021-01-25 Allogenic umbilical cord blood-derived mesenchymal stromal cell implantation was superior to bone marrow aspirate concentrate augmentation for cartilage regeneration despite similar clinical outcomes
HTO를 시행한 무릎 골관절염 환자에서 BMAC 대비 카티스템 투여가 연골재생에 더 효과적임.· 발행정보 | Knee Surg Sports Traumatol Arthrosc. 2022 Jan;30(1):208-218. doi: 10.1007/s00167-021-06450-w. · 저자 | Hong‑Yeol Yang, Eun‑Kyoo Song, Sung‑Ju Kang, Woo‑Kyoung Kwak, Joon‑Kyoo Kang, Jong‑Keun Seon |
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제대혈 | 2021-01-14 High Integrity and Fidelity of Long-Term Cryopreserved Umbilical Cord Blood for Transplantation
장기간 보관된 냉동제대혈의 안정적인 생존율 회복과 높은 기능적 우수성에 관한 연구· 발행정보 | J Clin Med. 2021 Jan 14;10(2):293. doi: 10.3390/jcm10020293. · 저자 | Gee-Hye Kim, Jihye Kwak, Sung Hee Kim, Hee Jung Kim, Hye Kyung Hong, Hye Jin Jin, Soo Jin Choi, Wonil Oh, Soyoun Um |
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카티스템 | 2021-01-12 Allogeneic Umbilical Cord Blood-Derived Mesenchymal Stem Cell Implantation Versus Microfracture for Large, Full-Thickness Cartilage Defects in Older Patients: A Multicenter Randomized Clinical Trial and Extended 5-Year Clinical Follow-up
카티스템 임상 3상 시험에서, 카티스템 투여는 골관절염 유무에 관계없이 연골 결손이 있는 환자에서 미세골절에 비해 최대 5년까지 통증 및 기능의 더 지속적인 개선 효능을 나타냄.· 발행정보 | Orthop J Sports Med. 2021 Jan 12;9(1):2325967120973052. doi: 10.1177/2325967120973052. · 저자 | Hong-Chul Lim, Yong-Beom Park, Chul-Won Ha, Brian J Cole, Beom-Koo Lee, Hwa-Jae Jeong, Myung-Ku Kim, Seong-Il Bin, Chong-Hyuk Choi, Choong Hyeok Choi, Jae-Doo Yoo, Cartistem Research Group; Jung-Ro Yoon, Jun-Young Chung |
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SMUP-Cell | 2021-01-03 Senescence-Associated Secretory Phenotype Suppression Mediated by Small-Sized Mesenchymal Stem Cells Delays Cellular Senescence through TLR2 and TLR5 Signaling.
작은 사이즈의 제대혈 유래 줄기세포이 SASP 활성화와 연관된 TLR2 및 TLR5 신호전달을 억제시켜, 세포노화를 지연시킴.· 발행정보 | Cells. 2021 Jan 3;10(1):63. doi: 10.3390/cells10010063. · 저자 | Ji Hye Kwon, Miyeon Kim, Soyoun Um, Hyang Ju Lee, Yun Kyung Bae, Soo Jin Choi, Hyun Ho Hwang, Wonil Oh, Hye Jin Jin |
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줄기세포 | 2020-12-26 Prospects for the therapeutic development of umbilical cord blood-derived mesenchymal stem cells.
다양한 질환 내 사용되고 있는 제대혈 유래 줄기세포의 우수성 및 치료제로서의 가능성에 관한 리뷰논문.· 발행정보 | World J Stem Cells. 2020 Dec 26;12(12):1511-1528. doi: 10.4252/wjsc.v12.i12.1511. · 저자 | Soyoun Um, Jueun Ha, Soo Jin Choi, Wonil Oh, Hye Jin Jin |
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카티스템 | 2020-10-17 Allogeneic umbilical cord blood-derived mesenchymal stem cells combined with high tibial osteotomy: a retrospective study on safety and early results
무릎 내측부 골관절염 환자에서 HTO와 결합된 카티스템 투여는 안전하며, 연골상태 개선을 나타냄.· 발행정보 | Int Orthop. 2021 Feb;45(2):481-488. doi: 10.1007/s00264-020-04852-y. · 저자 | Young-Woo Chung, Hong-Yeol Yang, Sung-Ju Kang, Eun-Kyoo Song, Jong-Keun Seon |
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카티스템 | 2020-07-27 Comparison of Bone Marrow Aspirate Concentrate and Allogenic Human Umbilical Cord Blood Derived Mesenchymal Stem Cell Implantation on Chondral Defect of Knee: Assessment of Clinical and Magnetic Resonance Imaging Outcomes at 2-Year Follow-Up
BMAC 및 카티스템 투여 모두 2년 F/U에서 무릎 연골결손상의 연골병변 치료에 안전하고 효과적임을 확인함.· 발행정보 | Cell Transplant. 2020 Jan-Dec;29:1-10. doi: 10.1177/0963689720943581. · 저자 | Dong Jin Ryu, Yoon Sang Jeon, Jun Sung Park, Gi Cheol Bae, Jeong-Seok Kim, Myung Ku Kim |
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줄기세포 | 2020-07-18 Galectin-3 Secreted by Human Umbilical Cord Blood-Derived Mesenchymal Stem Cells Reduces Aberrant Tau Phosphorylation in an Alzheimer Disease Model
hUCB-MSCs 및 hUCB-MSCs 분비단백질 Galectin-3가 알츠하이머병 모델에서 비정상 타우 과인산화를 감소시킬 수 있음을 제시함.· 발행정보 | Stem Cells Int. 2020 Jul 18;2020:8878412.doi:10.1155/2020/8878412 · 저자 | Hoon Lim, Dahm Lee, Wan Kyu Choi, Soo Jin Choi, Wonil Oh, Dong Hyun Kim |
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카티스템 | 2020-06-26 High tibial osteotomy with human umbilical cord blood-derived mesenchymal stem cells implantation for knee cartilage regeneration
HTO와 병용하는 카티스템 투여는 내측부 골관절염 및 내반변형 환자에서 연골재생을 향상시키는 효과적인 치료법임.· 발행정보 | World J Stem Cells. 2020 Jun 26;12(6):514-526. doi: 10.4252/wjsc.v12.i6.514. · 저자 | Jun-Seob Song, Ki-Taek Hong, Chae-Gwan Kong, Na-Min Kim, Jae-Yub Jung, Han-Soo Park, Young Ju Kim, Ki Bong Chang, Seok Jung Kim |